Those ancient bacteria drive you to focus on behaviors that will keep your meat alive and able to reproduce. I call these behaviors the three Fs: fear (fight off or flee from things that might kill you), feed (eat everything in sight so you have energy to fight off or flee from things that might kill you), and the other f-word that propagates the species. You spend a lot of time on these three priorities, don’t you? (Location 77)
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We’ve already seen that it’s possible to live to a hundred and twenty. The longest verified living person made it to a hundred and twenty-two, and there are scattered but unverified reports of a hundred and forty. (Location 89)
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While I wouldn’t consider those foods Bulletproof, it is fascinating that even back then people had an intuitive awareness that longevity stemmed not just from good genes or good luck, but rather from the environment inside of and around us. (Location 116)
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you want to live to a hundred and eighty, or even to an energetic eighty, it’s essential to look at your life and ask, “What’s going to make me forget to change the (proverbial) water?” (Location 127)
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Once you’ve learned how not to die, you’ll learn how to age backward with strategies ranging from simple to cutting edge that will add more years to your life and more life to your years. (Location 135)
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We tell ourselves that the one thing we can’t have more of is time, but that’s simply not true. I’ve seen firsthand how much more life these hacks can give you, both now and in the future. (Location 137)
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In my late twenties, I decided to invest 20 percent of my net income each year into hacking my biology with nutrition, supplements, lab tests, treatments, technologies, and whatever it took to learn more. (Location 155)
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I was well on my way to prematurely developing all four of the diseases most likely to kill you as you age—heart disease, diabetes, Alzheimer’s, and cancer—or, as I call them, the Four Killers. (Location 230)
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And what has posed a lethal threat to bacteria since the beginning of time? Mold. (Location 280)
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This is exactly what happens as you age, whether or not toxic mold is present in your life: Mitochondria function steadily declines, leading to an increase in free radicals, which damage your cells. (Location 285)
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But the cuts from bad choices or a toxic environment begin to add up from an early age—and they’re hurting you even if you’re not currently feeling their effects (such as weight gain, brain fog, muffin top, and fatigue). And it’s a lot easier to avoid damage to your mitochondria than it is to reverse it later. (Location 305)
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When you’re still young and exploding with mitochondrial energy, you can take some of these hits. (Location 321)
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Well, what if you made better choices throughout your life so you took fewer hits over the course of decades? Then when you got to the age of seventy you might look and feel more like fifty because you simply suffered less damage. (Location 326)
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When your mitochondria start to slow down and create an excess of free radicals, the result is widespread chronic inflammation throughout your body. (Location 330)
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Bacteria communicate with one another via chemicals (like hormones), light, or physical movement. They even gather around and trade bits of their genetic code in a microscopic swap meet for bacteria superpowers. (Location 357)
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“You are at a high risk for heart attack and stroke.” I recall the bewilderment and fear in my gut as I stared my own mortality in the face. (Location 367)
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My body was filtering out those signals to conserve energy because my biology was so trashed. Our bodies will always prioritize survival over socialization, and I didn’t have enough energy to go around. (Location 378)
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Recent research on mice has found that glucosamine promotes mitochondrial biogenesis (the birth of new mitochondria) and mimics the effects of calorie restriction.13 (Location 418)
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The good news is that researchers have been testing compounds that mimic the benefits of calorie restriction without the starvation. Glucosamine is one of those compounds. (Location 423)
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started eating more protein and avoiding grains and most obvious sources of sugar, for the first time focusing more on what I didn’t eat (carbs) than how much (Location 439)
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Dr. Daniel Amen, who was one of the first people in this country to use SPECT scans, was shocked that I had been even remotely successful in my career with such clear cognitive dysfunction. (Location 464)
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More than 40 percent of Americans are diagnosed with cancer in their lifetime.19 When mitochondria become dysfunctional and don’t produce energy efficiently—which, again, is typical of most people as they age—your risk of cancer increases. This is because an inflamed environment offers the perfect conditions for cancer cells to proliferate. (Location 473)
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We often think that our risk of developing cancer is based mostly on our genetics, but the data shows that only about 2 to 5 percent of cancers are truly genetically based, and mitochondrial dysfunction causes most others. (Location 480)
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Cancer is something of a double-edged sword when it comes to anti-aging. (Location 486)
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When you activate autophagy, you slow down the aging process, reduce inflammation, reduce your cancer risk, and increase your body’s ability to function at its best. There are specific supplements and lifestyle modifications such as brief bouts of fasting that boost autophagy. You’ll learn how to do this as we get deeper into the techniques that make you Super Human. (Location 495)
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Quick, picture a stereotypical “old person.” In your mind’s eye you probably see a frail person with loose skin, no muscle tone, (Location 561)
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